In a final effort to save the project, Pauling submitted one last application, noting the success of his experiments with
both animal and human patients. To aid his cause, Pauling attempted to find support at the source, sending individual letters
to key members of the CMR. In October 1944, the CMR responded to his requests for aid, providing a $10,000, nine-month grant.
The CMR had previously assured Pauling that the Committee would arrange any necessary physiological tests that could not be
completed at Caltech and, upon renewal of the Oxypolygelatin contract, they reaffirmed this promise.
While Pauling waited for the CMR to complete arrangements for testing, he and his team continued to refine the production
process, ironing out wrinkles that had developed over the course of their frantic experimentation. During the early months
of the Oxypolygelatin program, Pauling had corresponded often with Robert Loeb, a researcher at the College of Physicians
and Surgeons in New York. In a 1943 letter to Loeb he wrote, "It looks as though our method of preparation is not well enough
standardized to give a uniform product - the osmotic pressure varies from preparation to preparation. With some evidence from
the ultracentrifuge as to how the distribution in molecular weight is changing, we should be able to improve the method."
The lack of uniformity in the substance was a problem for Pauling and his team. In order to locate the irregularities, the
researchers needed results from a series of physiological tests. The CMR, however, had yet to arrange for the promised tests
and Pauling's grant was about to expire.