"[Using Robley Williams's] density, I calculated the number of polynucleotide chains per unit to be exactly three. This result surprised me, because I had expected the value two if the nucleic acid fibres really represented genes. I decided, however, that probably the fibres were artefacts, produced by the process of extraction...I am now astonished that I began work on the triple helix structure, rather than on the double helix."
Linus Pauling. "The Molecular Basis of Biological Specificity" Nature, 248: 771. 1974.

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