Activity Listings
- Letter from LP to Dr. Louis P. Hammett RE: Sends congratulations on the marriage of Hammett's son, who is recently returned from abroad. Notes that he and AHP hope to meet the son and his wife some time. [Filed under LP Correspondence: Box #151.8, file:(Hammett, Louis)]
- Letter from LP to Frank Blair Hanson, The Rockefeller Foundation RE: LP thanks the Rockefeller Foundation for extending the period of support for Sturtevant and his immunology work. [Filed under LP Science: Rockefeller Foundation, 1943-1962: Box #14.039 Folder #39.1]
- Letter from LP to Prof. J. Warren Williams, Dept. Of Chem., University of Wisconsin RE: Explains that their boy Linus wrote about his visits with Williams and his family, expresses gratitude for them looking after him, and regrets that he and AHP will be unable to see him very soon. Adds that his work on chemically treated gelatin is coming to a close, and they have put in an application for another contract with proposals of treating globin with other substances, mentions that they find William's Devards method increasingly useful. [Filed under LP Correspondence: 443.12]
- Letter from Linus Pauling to Dr. Dan Campbell. [Filed under: RNB 17R: Addendum]
June 27, 1944
Dr. Dan H. Campbell
Linus Pauling
Immunizing antigens
I suggest that we make an effort to find an immunizing antigen of known structure. Let us first take a synthetic resin of suitable nature, grind it up into very fine particles, and couple the particles with arsanilic acid or some similar group. These coupled particles would then be tested with anti-B serum, which should agglutinate them. If it does, some of the coupled resins could be injected into rabbits and guinea pigs to test immunizing antigenicity.
Perhaps the amberlites would be good resins to try in this way.
I think also that some dyes with very large molecular weight, such as Bismarck brown and nigrosine, should be coupled with arsanilic acid and tried in this way.
Linus Pauling
LP:jr
cc to David Pressman
|
June
27, 1944
