Letter from Linus Pauling to Hans Neurath. April 8, 1942. Page 1  Larger Images / More Information. 1 p.  View Transcript

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Activity Listings

• Letter from F. E. Wright, Home Secretary, National Academy of Sciences, to Members of the National Academy of Sciences. RE: Sends a report of the Nominating Committee for this year. Quotes verbatim a letter from W. Mansfield Clark listing the nominees fro Foreign Secretary and Councilors. Encloses a list of the present officers and members of the council. [Filed under LP Science: National Academy of Sciences, 1939-1944: Box #14.018 Folder #18.2]
• Letter from Harry V. Welch, Secretary, Southern California, to LP. RE: Trusts that all councilors will be able to attend the meeting in Memphis. Informs them that if they cannot attend, they should find a substitute. Requests to be advised on who can go and who is unable to. [Filed under LP Science: American Chemical Society: Correspondence, 1925-1942: Box #14.002 Folder #2.5]
• Letter from Kenneth B. Demaree, McGraw-hill Book Company, to LP . RE: Demaree would like to assure LP of McGraw-Hill's interest in publishing his chemistry text. They have heard that the manuscript will soon be ready, and they hope that LP will send it to them so that they might review the material. [Filed under LP Manuscripts of Books, 1947b5.15]
• Letter from LP to A.N. Clark, D. Van Nostrand Company, Inc., RE: LP says that he has completed the first thirteen chapters of the preliminary edition of his chemistry manuscript, but regrets to say that his work on the text will have to be delayed. He's become more involved in war research and no longer has the time to devote to work on the text, and so has decided not to make any definite arrangements regarding it. [Filed under LP Manuscripts of Books, 1947b5.21]
• Letter from LP to Dr. Hans Neurath, Department of Biochemistry, Duke University School of Medicine. [Letter from Neurath to LP March 27, 1942] [Filed under LP Correspondence: Box #276.8, file:(Neurath, Hans)]

  April 8, 1942

  Dr. Hans Neurath

  Department of Biochemistry

  Box 3711

  Duke University School of Medicine

  Durham, North Carolina

  Dear Dr. Neurath:

  I was glad to receive your letter of March 27, and to learn of your program of physical-chemical study of the effect of heat treatment of globulin fractions. I do not believe that this work which you plan will duplicate in any significant way the work that we are doing and plan to do. We are carrying out an extensive series of investigations, but not along exactly these lines.

  You were right in thinking that my picture of denaturation involves unfolding of protein molecules, rather than increase in solvation. As a matter of fact, I do not have any clear picture of what is meant by increase in the degree of solvation. It seems to me that change in degree of solvation would be subsidiary to some other change, and not itself fundamental.

  We have made antibodies in vitro by the use of heat, and also by other methods, such as alkali denaturation and slow renaturation. Our investigations are not sufficiently complete to tell whether there is close similarity or considerable difference in the antibodies obtained by these different methods. We are of course going on with the work as rapidly as possible, and we shall publish the results as fast as they are obtained. A brief account, just an outline, is to appear in Science next week, and I shall send you a reprint of it. A more detailed account of the work done so far will appear probably in the Journal of Experimental Medicine. Several papers on our other experiments are to come out soon in the Journal of the American Chemical Society, and one in the Journal of Immunology.

  With best regards, I am

  Sincerely yours,

  Linus Pauling

  LP:jr

• Letter from LP to Dr. Henry P. Treffers, College of Physicians and Surgeons. RE: Understands why Treffers declined the appointment. Hopes he will be able to accept on a future date. [Letter from Treffers to LP April 3, 1942] [Filed under LP Science: Materials re: Antibody and Antigen Research; the Nature of Serological Reactions, 1940-1947, 1950-1952, 1973, 1986: Box #7.001 Folder #1.1]
• Letter from LP to Dr. Michael Heidelberger, College of Physicians and Surgeons, Columbia University, RE: Notes he was sorry to learn that Treffers could not take the appointment at Cal Tech. Mentions that Dr. Campbell is teaching in Chicago for a term. Regrets that Ikeda will be sent to a camp in two weeks, and adds that they have appointed new assistants in immunochemistry. [Letters from LP to Heidelberger March 25, 1942, from Heidelberger to LP April 20, 1942] [Filed under LP Correspondence: Box #153.3, file:(Heidelberger, Michael)]
• Letter from LP to Dr. Michael Heidelberger, College of Physicians and Surgeons. RE: Sorry to hear that Treffers has turned down the appointment. Discusses the upcoming year and who will be working in Pasadena. [Filed under LP Science: Materials re: Antibody and Antigen Research; the Nature of Serological Reactions, 1940-1947, 1950-1952, 1973, 1986: Box #7.001 Folder #1.1]
• Letter from LP to Dr. W. M. Stanley, The Rockefeller Institute for Medical Research RE: Thanking Stanley for tube with tobacco mosaic virus, which arrived safely. Dr. Pressman is starting at once on the tested preparation of antisera against the virus. LP has not checked Ostromuislenskii's experiments yet. [Stanley's letter April 2, 1942] [Filed under LP Science: Rockefeller Foundation, 1936-1946: Box #14.038 Folder #38.10]
• Letter from LP to Edward Barrett. RE: Asks that Reuben Wood and Herbert Sargent be paid half from NDRC-Chem-1b and half from Chemistry Special. [Filed under LP Science: Scientific War Work - Materials re: the Pauling Oxygen Meter, 1942-1950: Box #13.002 Folder #2.1]
• Letter from LP to Harry Wood, Ginn and Co., RE: LP thanks Wood for his interest in publishing LP's manuscript and apologizes for the change of plans. He says that due to the national situation, he will be more invested in war research and won't have time to devote to his manuscript. [Filed under LP Manuscripts of Books, 1947b5.10]
• Letter from LP to R.H. Thornton, Ginn and Co., RE: LP apologizes for the delay in his reply. He says that in response to his trip to Washington, he knows he will be required to devote a much larger potion of his time to war research, and feels that he can not enter into a publishing contract at this time. [Filed under LP Manuscripts of Books, 1947b5.10]
• Letter from LP to The President and Council. RE: Informs them that he is unable to attend the Franklin Medal Lecture. [Filed under LP Science: American Philosophical Society, 1936-1963, 1989, 1991: Box #14.011, Folder #11.1]
• Letter from Prof. Joel Hildebrand, Department of Chemistry, UC Berkeley, to LP RE: Sends a copy of a thesis by Robert Long concerning the polymer research. Requests LP look it over and send it back with comments. Adds supplemental figures as a postscript in ink. [Letters from LP to Hildebrand April 2, 1942, June 1, 1942] [Filed under LP Correspondence: Box #159.3, file:(Hildebrand, Joel)]
• List of the Officers and Members of the Council of the Academy. [Filed under LP Science: National Academy of Sciences, 1939-1944: Box #14.018 Folder #18.2]