Letter from Linus Pauling to Karl Landsteiner. July 15, 1940. Page 1  Larger Images / More Information. 1 p.  View Transcript

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Activity Listings

• Letter from Dr. Norris W. Rakestraw, Editor, Journal of Chemical Education, to LP RE: Thanks him for agreeing to do a series of collaborative papers at a later date. Reiterates the interest his readers would have in such a series. [Letters from LP to Rakestraw July 2, 1940, from Rakestraw to LP March 26, 1941] [Filed under LP Correspondence: Box #191.4, file:(Journal of Chemical Education )]
• Letter from Dudley Williams, to Dr. Lamb, Editor, Journal of American Chemical Society. RE: Has read with interest the comments on the manuscript entitled “The Infrared Spectra of Ammonium Halides.” Replies to certain points mentioned by the referee. [Filed under LP Science: American Chemical Society: Correspondence, 1925-1942: Box #14.002 Folder #2.5]
• Letter from LP to Dr. Karl Landsteiner, Rockefeller Institute for Medical Research. [Letter from LP to Landsteiner July 2, 1940, Note from Landsteiner to LP July 19, 1940] [Filed under LP Correspondence: Box #212.7, file:(Landsteiner, Ernest Karl)]

  July 15, 1940

  Dr. Karl Landsteiner

  Newfane, Vermont

  Dear Dr. Landsteiner:

  Your serum and antigens arrived safely, and Dr. Campbell and I have begun experiments with then, with however no results of interest so far.

  I have thought of an experiment which might he of great interest in showing the presence or absence of antibodies with two kinds of complementary regions, and I am writing to you now to ask if the experiment has ever been carried out. I notice that AB erythrocytes are completely agglutinated by either α serum or β serum, and I suppose also by rabbit antibodies to either A or B erythrocytes. This shows that AB blood contains corpuscles which individually possess both A and B groups. Hence we would predict that rabbit antibodies to these corpuscles would be of three kinds, α-α, β-β, and α-β. Now the following experiment should test for the presence of α-β. Let some A erythrocytes be treated with an excess of AB antiserum, sufficiently great so that agglutination does not occur, each erythrocyte being completely coated with antibodies. Let these coated cells be washed and then added to a suspension of B erythrocytes. If the serum contained α-β antibodies, agglutination of the cells should occur. If not, there should be no agglutination. A similar experiment could be carried out with serum of O type blood, to test for the presence of α-β antibodies in this serum. Can you tell me whether this experiment has been carried out and with what results? If it has not been done, I would plan to do it.

  With best regards, I am

  Sincerely yours,

  Linus Pauling

  LP:jr

• Letter from LP to Dr. T. L. Swenson, Director, Western Regional Research Laboratory, U.S. Dept. of Agriculture, RE: Thanks Swenson for the last letter and looks forward to seeing Swenson when he comes to Pasadena. [Letter from T. L. Swenson to LP July 12, 1940] [Filed under LP Correspondence: #377.10]
• Letter from LP to Dr. Thomas Addis RE: Responds to Dr. Addis' recommendation of Dr. Mirsky expressing that Mirsky will most likely continue in research due to his appointment as Associate Member of the Rockefeller Institute. [Note from Dr. Addis to LP (undated 1940)] [Filed under LP Correspondence: Box #2.1, file:(Addis, Thomas 1940-1945)]
• Letter from LP to Warren Weaver, The Rockefeller Foundation RE: Thanking Weaver for his response to LP's MS on antibodies and updates him on the progress of immunological experiments in the lab. LP is enjoying having Campbell in the lab. [Weaver's letter to LP July 9, 1940; Reply July 19, 1940] [Filed under LP Science: Rockefeller Foundation, 1936-1946: Box #14.038, Folder #38.9]
• Letter from Thomas Anderson to LP RE: Thanks him for the letters written on his behalf and informs him that the position in Cincinnati appears to be primarily in teaching mathematics. States that he gave a talk on the vibrational Raman effect and wonders if LP could critique an abstract for the Detroit meeting of the A.C.S. Asks him to keep looking for more employment possibilities. [Filed under LP Correspondence: Box #6.8, file:(Anderson, Thomas, 1939-1945)]