"I remember asking a new graduate student, Harvey Itano, what his research problem was. He said he was going to test your hunch that there was a difference in hemoglobin molecules between normal people and those with sickle cell anemia. I thought that was a crazy idea; a complicated human disease could not have any such simple cause. And so I learned to respect bold simple ideas -- especially those conceived by Linus Pauling."
Norman Davidson. Letter to Linus Pauling. January 26, 1976.

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